GSAA: Gene Set Association Analysis

GSAA is a computational method that integrates gene expression analysis with genome wide association studies (GWAS) to determine whether a priori defined sets of genes shows statistically significant, concordant differences with respect to gene expression profiles and genotypes between two biological states. Gene sets are generally a group of genes, such as genes in a biological pathway, that are putatively functionally related, co-regulated, or tightly linked on the same chromosome.